Lassen is developing novel antibodies with the goal of creating transformational medicines.
Our lead program is a clinical-stage first-in-class monoclonal antibody to block the IL-11 pathway.
IL-11 is a novel target with a central role in fibro-inflammatory signaling, distinct from other factors such as TGF-β, CTGF, and IL-13. Inhibition of IL-11 represents an alternative to targeting signal transducing kinases and intracellular transcription factors and has applications in high unmet needs in fibro-inflammatory diseases, including idiopathic pulmonary fibrosis and thyroid eye disease.
